After updating your Trend Micro definition to pattern 12.941.00 the following file in SharePoint will be quarantined because the antivirus Software incorrectly identifies that this files contains JS_NEMUCOD.SMAA15:
C:\Program Files\Common Files\Microsoft Shared\Web Server Extensions\15\template\layouts\1033\initstrings.js.
While rendering a SharePoint site or list you may receive a 304 or a server error in Application /
In ULS you will see a message similar to:
Cannot make a cache safe URL for "15/1033/initstrings.js", file not found. Please verify that the file exists under the layouts directory.
Description: An unhandled exception occurred during the execution of the current web request. Please review the stack trace for more information about the error and where it originated in the code.
Exception Details: Microsoft.SharePoint.SPException: Cannot make a cache safe URL for "15/1033/initstrings.js", file not found. Please verify that the file exists under the layouts directory.
Trend Micro has released a new pattern to correct this (pattern 943): http://downloadcenter.trendmicro.com/index.php?clk=tab_pattern&clkval=35®s=NABU&lang_loc=1
Customers should also ensure that they have the correct Antivirus Exclusions in place on their SharePoint servers as per https://support.microsoft.com/en-in/kb/952167. Depending on how the antivirus software is configured (quarantine or delete), it might also be required to replace the affected files if they were deleted.
In case that Trend Micro anti virus is used on client machines, the pattern on the client machines also has to be updated to ensure that the file is not quarantined when browing to a SharePoint site.
[Update December 7th, 2016] We have now an KB article for this issue as well: https://support.microsoft.com/en-us/kb/3211219