Quick Solution 8: The located assembly's manifest definition does not match the assembly reference while managing User Profile Service
Symptoms
After started the User Profile Synchronization Service, when you try to manage the User Profile Service, you encounter an error, and the following error is logged in the SharePoint Unified Logging Service (ULS).
Error Message
<date time> w3wp.exe (0x1F88) 0x1AA4 SharePoint Portal Server User Profiles
et8j High UserProfileServiceUserStatisticsWebPart:LoadControl failed, Exception: System.IO.FileLoadException: The located assembly's manifest definition does not match the assembly reference. (Exception from HRESULT:0x80131040)
at Microsoft.Office.Server.UserProfiles.UserProfileConfigManager.InitializeIlmClient(String ILMMachineName, Int32 FIMWebClientTimeOut)
at Microsoft.Office.Server.UserProfiles.UserProfileConfigManager..ctor(UserProfileApplicationProxyuserProfileApplicationProxy, Guid partitionID)
at Microsoft.SharePoint.Portal.WebControls.UserProfileServiceStatisticsWebPartBase.LoadControl(Object sender, EventArgs e)
Causes
The issue is caused by that, the UserProfileConfigManager adds a reference to Microsoft.ResourceManagement, but the located Microsoft.ResourceManagement assembly's manifest definition does not match the assembly reference.
Solutions
To fix the issue, please restart the Internet Information Server(IIS) by running command iisreset.