Conficker worm is widespread throughout the world. Below is some information that will help to identify , fix and resolve the problem. Note that detection & cleaning of the worm is taken into account with the latest Microsoft Forefront Client signature.
Security Bulletin :
http://www.microsoft.com/technet/security/Bulletin/MS08-067.mspx
Summary , Analysis , Prevention and Recovery :
http://www.microsoft.com/security/portal/Entry.aspx?Name=Worm%3aWin32%2fConficker.B
Good News for ISA Customers : There are scripts available publically from http://www.isatools.org/tools.asp?Context=ISA2006 , http://www.isatools.org/tools.asp?Context=ISA2004 à “block_conficker.vbs” which will block the worm at perimeter level itself