I manage a local schools infrastructure in my spare time and they had this strange little issue:
After a power outage, the information store on my Exchange 07 SP1 server (running Windows 2008) would not start. All other services were running ok and running the following command:
SC Query MSExchangeIS
I could see the following:
State : 0 Stopped
Win32_Exit_Code : 1066 (0x42a)
Service_Exit_Code : 0 (0x0)
Checkpoint : (0x0)
Wait_Hint : (0x0)
I did some research and it appeared that it may have been AV orientated, so I went into the following registry key:
The key is HKEY_LOCAL_MACHINE\SYSTEM\Current Control Set\Services\MSExchangeIS\VirusScan\Enabled
Current value 1 changed to 0
This allowed the service to start and all email was fine.
I have now re-installed my AV and it all appears to be back to normal and the enabled is now back at 1.