People have been asking on our forums if Forefront Protection 2010 for Exchange Server (FPE) can be run in a Hyper-V virtual environment. The short answer is yes. The deployment, configuration, and operation of FPE are the same in Hyper-V virtual server environments as on physical servers.
For details about installing in and running in a Hyper-V virtual environment, read our documentation on TechNet: http://technet.microsoft.com/en-us/library/dd639345.aspx
Michel LaFantanoForefront Server Protection UA