Reading SlashDot this morning and ran across this great article. Researchers are developing new interfaces or modifying existing ones to allow the blind and those with missing limbs to be able to take part in the Guitar Hero phenomenon.
In the IEEE article that SlashDot links to, they are utilizing modified controllers to assist with training arm amputees with learning how to use their new prosthetic limbs. Way Cool!
Watch the video linked to for the open source Frets on Fire that has been modded to allow for a haptic glove to be used for sensing the coming notes. The smile on the players face as he plays says it all!