Making the Most of App-V 4.6 Support for 64-bit Virtual Applications and 64-bit Operating Systems

TipThe App-V 4.6 beta was just released on Monday and we are excited to have released the product we have been working on for the past few months to our customers. Throughout the week, we have received a number of questions about what is supported between 32-bit and 64-bit sequencing, along with running the sequenced applications on the 32-bit and 64-bit App-V client, so I wanted to address those questions and share more details with everyone here.

Our vision for App-V 4.6 is to allow you to keep all of your existing sequencing investments and be able to leverage 64-bit moving forward, in a simple and straight forward manner. 

With that in mind, the following are some general guidelines about what is supported:

Existing packages:

All your pre-4.6 packages are valid and can continue to be used on the 4.6 client – just modify the OSD file to include the OS values for the 32 and/or 64-bit platform as target, as appropriate.

For new 32-bit applications to be run on the 4.6 client:

Sequence the 32-bit app on a 32-bit OS using the 4.6 sequencer. Specify x86 and x64 platforms as targets as appropriate for clients.

Note: App-V will not support running 32-bit applications on a 32-bit OS, if they were sequenced on a 64-bit OS sequencer machine.

Note: New 32-bit applications sequenced with the 4.6 sequencer are NOT supported on 4.5 client as indicated in the support matrix below.

For new 64-bit applications to be run on the 4.6 client:

Sequence the 64-bit app on a 64-bit OS using the 4.6. sequencer. Specify x64 as the target platform.


We welcome you to try these out with our Beta Release (available on If you encounter any issues or have any comments, you can report it through the connect site and that will be directed straight to the App-V engineering team.

We are looking forward to your feedback and input on App-V 4.6.

Lidiane Souza | App-V Group Program Manager

Comments (1)

  1. Anonymous says:

    So, then, what do I need to add to my existing 4.5 sequences’ OSD to make them available to 64-bit 4.6 clients?

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