If you're anxious to begin the planning and implementation of App-V 4.5 then this one's for you. Our Infrastructure Planning and Design guides have been updated to include Microsoft App-V 4.5 and they're available either as a complete series or as individual guides here.
If I was wearing my marketing hat I'd probably say that "The new Microsoft Application Virtualization 4.5 guide provides you with key information to bring your infrastructure up to date, saving you time and money. Find out how App-V’s HTTP streaming of virtual applications from an IIS server will impact your performance and scalability decisions. Using App-V 4.5 with its many new features to strategically plan your application virtualization infrastructure can help you avoid problems before they begin, allowing you to serve your customers more accurately and reliably."
You can find the new App-V 4.5 IPD guide as well as IPD guides for OpsMgr 2007, Active Directory, IIS and much much more at http://www.microsoft.com/downloads/details.aspx?FamilyId=AD3921FB-8224-4681-9064-075FDF042B0C&displaylang=en.
J.C. Hornbeck | Manageability Knowledge Engineer